Purly Imaginative Subject by Gary J. Kornblith - 933 Words

An essay written by Gary J. Kornblith, the main focus is on a purely imaginative subject. The use of this counterfactual approach is widely accepted as a methodology in research of causation. According to Kornblith, counterfactual exercises are necessary to â€Å"think more clearly about causation and to distinguish between essential factors and coincidental developments†(79). He uses the counterfactual method to present the idea that if Henry Clay had been elected in 1844, which he goes on to prove as plausible, we would be in a much different country. The thesis as a whole is stated as â€Å"†¦ My focus is on a different pair of wars: the Mexican-American War of 1846-1848 and the American Civil War of 1861-1865†¦ Rather than project a different military outcome, I posit the absence of the Mexican-American War†¦The key to peace in my counterfactual scenario is a victory by Henry Clay over James K. Polk in the very close presidential election of 1844†¦ As a result Texas would almost certainly have remained an independent republic in 1845, and the United States would not have gone to war with Mexico the following year. Based as it is on a highly plausible turn of events, this counterfactual scenario promises to advance our understanding of the causes of the Civil War†(77). He then adds the fact that there are two viewpoints that come from this counterfactual exercise; Revisionists, who believe that the Civil War could have been avoided, despite the sectional differences, and

Employee Participation Free Essay Example, 1500 words

According to Markey Townsend, employee participation also saves time for the management by involving in the matters that can be resolved by the employees themselves. Through participation, communication and cooperation among the organizational members improve gradually and thus, they can communicate regarding any issue and solve them without involving the management, which in turn saves time. Moreover, it is found among the participative workers the tendency to supervise themselves. This also helps in saving the time of the management as well as cut down the overhead cost of labor (Han et. al. , 2010). Employee s sense of dignity and power is also enhanced through participation in the decision-making process and therefore, the risk of dissatisfaction among the employees decreases that further increases performance of the organizational activities and eliminates conflict with the management. Barney Wright (1997) also stated that involving the employees in the decision-making proce ss of the organization enhances their commitment and loyalty towards the organization. Markey Townsend (2015), further noted that if the management and the employees jointly coordinate with each other in solving problems, the issues would be resolved in an effective manner. We will write a custom essay sample on Employee Participation or any topic specifically for you Only $17.96 $11.86/page The important decisions of an organization are generally made by the top-level management along with collaboration with other higher-level authorities.

Clothing Company Should Have Kept Their Domestic...

Balagny Clothing Company should have kept their domestic operations within the country rather than outsourcing the work to China and Mexico. I understand that companies want to cut cost and find ways to lower their expenses and gain profits but when outsourcing to other countries, there will be several factors that are tied into play. Wages are not the only thing that weighs on the decisions which is what Balagny Clothing Company made a decision off of. Sure the wages of China and Mexico are much cheaper and cost effective but the inconvenience of shipping, having to deal with foreign contractors through managerial role, the lack of logistics, environmental forces that come into play, country’s regulations and laws, etc. Is it really worth outsourcing operations just to save on wages and provide more headaches when we need to deal with problems with a foreign country. When companies outsource the manufacturing jobs to foreign countries, the US will take a direct hit of the blo w. Millions of workers will lose their jobs to the foreign country and the United States economy will suffer losses as well. According to AmericanProgress.org â€Å"Manufacturing employment collapsed from a high of 19.5million workers in June 1979 to 11.5 workers in December 2009, a drop of 8 million workers over 30 years.† That alone is a huge number considering that manufacturing jobs were the driving force of the United State economy for decades. Balagny Clothing Company will be just like otherShow MoreRelatedThe Importance Of A New Leader Elected Or Placed At Office Within The Countries Of The World1662 Words   |  7 Pagesplaced in office within the countries of the world. Sometimes leaders clash on their beliefs on how the country should be run, including the companies that conduct business in and with the country. Coca-Cola will have to be diligent in remaining aware of these leaders and their agendas. Changes will come, and some will not be beneficial to the company . The company must be aware of these changes in order to develop strategy for operations within those countries. Otherwise, the company could find itselfRead MoreEssay about Le Chateau5253 Words   |  22 PagesOrganizational Introduction Company Overview Positioning Financial Performance External Analysis Porter’s Five Forces Analysis Internal Analysis Resources Capabilities Strategic Analysis Business-Level Strategy Corporate-Level Strategy Objectives amp; Alternative Courses of Action #1: Alter Manufacturing Process #2: Strategic Alliance #3: Global Expansion #4: Acquisition Recommendation Works Cited Appendix Interview Organizational Introduction Company Overview Le Chateau isRead MoreInternal And External Factors That Influence A Company s Operating Situation Essay2066 Words   |  9 Pagesstart saving their money when the interest rate are high which will make them spend less It will cost more to export and import from other countries. Labour to Conservative change. Zero-hour contract Brexit Recession No more grants for university students Review Business environment The combination of internal and external factors that influence a company s operating situation. The business environment can include factors such as: clients and suppliers; its competition and owners; improvementsRead MoreEssay about North American Free Trade Agreement: Nafta1764 Words   |  8 Pagesworld economy due to technological advances in computers and communications have shrunk the world to the point where no single country acting alone can effectively compete on the foreign market. Even the United States, with its vast resources, can not have an absolute advantage in all thing that it produces. It does not have unlimited factors of endowments and must do its best to make these available to the companies within its borders. nbsp;nbsp;nbsp;nbsp;nbsp;There are two basic sides to theRead MoreWto and Its Impact on Indian Economy11045 Words   |  45 Pagespermitted exceptions. 2. 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Through reviewing the RMB exchange rate system’s reform process in recent years, this article amylases its positive and negative effects for import and export trade in our country, especially the influence on China s main export industry, and the continued RMB appreciation under the trend of study of China s foreign trade policy adjustment, at the same time give suggestion to both government and enterprises. Key word: RMBRead MoreZara Fast Fashion: Executive Summary5256 Words   |  22 Pagesin the fashion clothing industry. Zara adopts international strategy for its operation. With vertical integration, it benefits Zara in cost aspect, however, it involves some risks. Due to our anaylysis on Zara’s operations, some of the recommendations are made to facilitate its further improvements. Marco-environment Macro-environments are changing in different aspects which influence Zara’s operation. Demographic:Age structure Age structure changes nowadays. Most countries have majority of adultsRead MoreHM Accounting Analysis Report2940 Words   |  12 Pages Business Analysis Overview The Swedish company Hennes Mauritz AB is the second largest clothing retailer in the world, just behind Spain-based Inditex (parent company of ZARA). The HM Group’s business consists mainly of sales of clothing, accessories, footwear, cosmetics and home textiles to consumers. In addition to HM Home, the group also owns several brands, as shown here, which make the company well-known for its fast-fashion clothing offerings for women, men, teenagers and children

The Effect Of Ultrasound Imaging On The Quality Of Medical...

Ultrasound imaging is one of the popular, cheapest and noninvasive medical scans. During the time of image acquisition, there is distortion of the quality of image in the form of speckle noise. Now a day, many researches made various experiments to enhance the quality of medical image. But still there is scope to enhance the image. In the proposed method, finding out the seed pixel randomly is basic issue, is treated as an optimization problem, it can be solved by Particle swarm optimization. Using particle swarm optimization algorithm , the fitness function can give us appropriate seed pixel for required ultrasound imaging .In this paper, a novel method wherein segmentation will be applied on the filtered image i.e fuzzy filter. Fuzzy filter basically work on fuzzy rules to detect on different gradient and then filtering the noisy , homogenous and edge region. The proposed method has been tested on different images, and the experimental results demonstrate its effectiveness. Keywords – PSO Particle swarm optimization,basic gradient ,fuzzy filter,global best, local best. Introduction Ultrasound imaging has been considered as one of the most powerful techniques for imaging organs and soft tissue structures in the human body. However, the presence of random speckle noise makes human interpretation and computer-aided ultrasound image diagnosis a highly difficult task. Thus it is necessary that we remove speckle noise from the images before they are processed further.Show MoreRelatedAbstract : Ultrasound Imaging And Its Effect On The Quality Of Medical Image2461 Words   |  10 PagesAbstract – Ultrasound imaging is one of the popular, cheapest and noninvasive medical scans. At the time of image acquisition, there may be distortion of the quality of image in the form of speckle noise. Nowadays, many researches have made various experiments to enhance the quality of medical image. However, there is scope to further enhance the image. 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This is done using strong magnetic fields and radio waves. It is a heavy equipment which uses advanced technology and many computer systems. The nuclei is polarised using the magnetic fields provided by the electromagnets and a hugeRead MorePhysics Assignment : Medical Imaging1672 Words   |  7 PagesKathleen Anne Maguire 1/12/2016 Physics Assignment Medical Imaging MDPMS 1. Sound is travelling from material 1 to material 2. The density of material 1 id 25 kg ms-3 and the density of material 2 is 18 kg m-3. The speed of sound in material 1 is 1900 ms-1 and in material 2 is 18 kg m-3. The speed of sound in material 1 is 1900 ms-1 and in material 2 it is 700 ms-1. The acoustic impedance of each material Z= pV Acoustic impedance (Z) Density is (p) Acoustic Velocity (V) ForRead MoreThe Importance Of Echocardiography For Clinical Practice As They Are Used For Screening, Diagnosis, And Diagnosis2604 Words   |  11 Pagesinvolved in image production. Echocardiography is based on the Principles of Wave transmission (Ultrasound) and The Doppler Effect which are considerably cheaper compared to X-ray imaging, CT, MRI, nuclear medicine and other diagnostic techniques (Cootney, 2001). In addition to cost, ultrasound cardiac imaging machines are relatively small and mobile which can also satisfy the requirements of measuring the cardiac function fast and accurately. Physics principles of Echocardiography Ultrasound are simplyRead MoreCase Analysis: Disruptive Technology a Heartbeat Away: Ecton, Inc.1250 Words   |  5 PagesCannon proposed a path for the next year containing five major points (Edward, 1999, 8 and 9). The bottom line of this proposal is positioning Ecton to be acquired by the end of the 1998. One of the crucial concerns of this acquisition is the possible effects on â€Å"Ecton’s product development process†. 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Both within trauma and non-trauma adult patients. This section of the review will explain the topic and reasoning into why it was done. The process of its relevance into radiography in practise will also be outlined. This will provide background into positive aspectsRead MoreUsing The Pulse Echo Principle ( Venables 2011a )3361 Words   |  14 PagesSound is a mechanical wave, propagating through a medium in order for it to travel (Venables 2011a). Ultrasound is defined as high frequency sound waves, above the audible range i.e. 20 kHz (Zidan et al. 2011). These waves are formed using the pulse-echo principle (Venables 2011a). This principle refers to the piezoelectric crystals which are situated in the transducer. When an alternating electrical voltage is applied across the transducer element (Lieu 2010), the element undergoes a series of

Developing Negotiation Case Studies Free Essays

While a great deal of excellent advice exists for producing case studies on managerially relevant topics in general, negotiation cases have distinctive aspects that merit explicit treatment. This article offers three types of tailored advice for producing cases on negotiation and related topics (such as mediation and diplomacy) that are primarily intended for classroom discussion: 1) how to decide whether a negotiation ­related case lead is worth developing; 2) how to choose the perspective and case type most suited to one’s objectives; and 3) in by far the longest part of the discussion, ten nuts and bolts suggestions for structuring and producing an excellent negotiation case study. Suppose you read about, participate in, or otherwise become aware of a negotiation that intrigues you as a possible candidate for a case study. We will write a custom essay sample on Developing Negotiation Case Studies or any similar topic only for you Order Now Perhaps a student, colleague, participant in an executive program, or private client suggests such an episode. You may consider researching and writing up the case yourself or you might supervise someone else for this purpose. Should you proceed with an investment of your scarce time and resources? If so, how? What’s the best casewriting advice you can give to a research assistant, a student (team) grappling with a course assignment to produce a case study, or someone else who is simply interested in writing up a negotiation for discussion purposes? ii Generations of experienced, even legendary, casewriters have codified guidelines for producing excellent case studies on virtually any subject. iii Yet negotiation cases often have distinctive aspects that merit explicit treatment. Over the years, I’ve found myself in many conversations trying to crystallize and convey the elements that seem to contribute to crafting superior negotiation cases. I hope that pulling these insights together and developing them a bit more systematically will be useful for others undertaking casewriting projects. A quick caveat: though casewriting is often properly part of a larger research program, and synergistic with other methodologies, I focus here on case studies that are mainly intended as vehicles for classroom discussion and analysis. As such, I sidestep important issues associated with systematically selecting and developing cases for well- defined research projects. For example, in the field of international relations, which thrives on case studies, the â€Å"method of structured, focused comparisons† is a research staple. iv More generally, exacting criteria exist for identifying, developing, comparing, and Draft: Developing Negotiation Case Studies. Copyright  ©2010 by James K. Sebenius. 1 contrasting case studies in order to extract valid inductive social scientific knowledge. However, I leave that set of considerations for specialists with casewriting as a component of well-defined research agendas. vi The following sections offer three types of advice for producing cases that are primarily intended for classroom discussion: 1) how to decide whether a case lead is worth developing; 2) how to choose the perspective and case type most suited to your objectives; and, 3) in the by far the longest part o f the discussion, ten nuts and bolts suggestions for structuring and producing an excellent case study. One of the best ways to learn the casewriter’s craft is to study a number of truly excellent case studies, or better, to discuss such cases in a forum led by an experienced case method instructor. As such, in each of the three advice sections that follow, I’m tempted to list a number of my favorite negotiation cases as models. Since, however, these choices may be unfamiliar to many readers, and may be set in times, places, or contexts of little interest to others, I will instead offer a set of model cases, plus commentary, in an online forum in the hope that others will consult, comment, and contribute. (See online url to be provided later. ). I. Advice on developing a prospective case: a case for what? A case of what? Start by seeking clarity on your overall purpose: â€Å"a case for what? † How to cite Developing Negotiation Case Studies, Papers

Treatment of Essential Dystonic and Parkinsonian Tremor - Samples

Question: Discuss about the Treatment of Essential, Dystonic and Parkinsonian Tremor. Answer: Significance of the study: The term tremor can be described as the uncontrolled rhythmic movement of the limbs or any part of the body. It has been estimated that, there are more than 100 million patients worldwide who suffers from tremor (Baumann 2012). The disease can be evidently seen among the older individuals who often suffer from many motor symptom disorders such as Parkinsons disease, Alzheimers and Huntingtons disease. Many individual of young age can also suffer from tremor due to many reasons such as psychological trauma, tension, depression and anxiety (Gallego et al 2013). Apart from the neurological disorders, tremor can also happen due to thyroid disorders, stroke, multiple sclerosis, substance abuse, mercury poisoning and anxiety. Research strategy: Many keywords such as tremor, Parkinsons disease, psychogenic tremor, task specific tremor, beta-blocking drugs, dystonic tremor, physiologic tremor, psychogenic tremor, cerebeller tremor and essential tremor have been used to search some online database such as CINAHL, Cochrane, Medline and Scholarly. Searching all these sites was helpful as it presented more than 800 articles regarding tremor to access. All the relevant materials are accessed and three articles from the database were chosen based on the relevance. These articles are Treatment of essential tremor: a systematic review of evidence and recommendations from the Italian Movement Disorders Association (Article 1), The treatment of dystonic tremor: a systematic review (Article -2), and Beta- Blocker therapy for tremor in Parkinsons disease ( Article 3) respectively. Brief description: All three articles has discussed about the types of tremor and broadly described about different aspects of the treatment of tremor. From these articles, this is evident that there are varieties of treatment options for tremor. Beta-blockers are used to treat essential tremor and anxiety related tremors. All three of the articles discuses the use of Beta-blocker as the treatment of tremor caused by Parkinsons disease. These articles also discuss using other drugs such as anticholinergies, primidone, tetrabenazine and clonazepam as the treatment of dystonic tremor (Kim et al 2014). All these studies compare the efficacy and safety of the drugs used for the treatment of tremor. Results of these studies have been found after experimenting with very small number of population, so it is difficult to make a conclusion. The quality of evidence of these drugs with respect to the controlled study with placebo was found to be very low to moderate. Definition of key terms: Tremor: Tremor can be defined as oscillatory, uncontrolled rhythmical movement of any body part such as limbs. The involuntary contracting movement of the innervated muscles causes tremor. Many types of tremors can be identified by using many parameters such as location, frequency and rthythmicity. Physiologic tremor: This is one of the kinetic action tremors, which happens to the normal individuals. This can be seen to the individuals suffering from physical exhaustion or is experiencing strong psychological emotion such as anxiety and withdrawal symptoms. Psychogenic tremor: It can happen to any condition, at rest or in kinetic movement. This type of tremor onsets and stops suddenly. This generally happens due to the occurrence of stress and suddenly relapses when the patient is distracted from the stress. Dystonic tremor: This type of tremor can be seen in individuals of every age affected with dystonia ( a disease in which the muscles of the body twitches and twirls repetitively). Dystonic tremor may affect any of the body muscles and causes painful postures (Fasano, Bove and Lang 2013). Essential tremor: This is the most common part of tremor, which can be seen in normal individuals. This tremor is commonly non-progressive but it might be progressive for some people (Song et al, 2015). This type of tremor is most commonly seen in the hands, but it can affect the other body parts such as tongue, legs and voice and head. Severity of this type of tremor essentially increases with the age of the person experiencing this. Parkinsons disease: Parkinsons disease is one of the most common degenerative disorders, which can be seen in the elderly. The central nervous system of the body gradually degenerates along with the age of the person and affects the central nervous system of the body (Jimnez, and Vingerhoets 2012). Resting tremor is often a precursor of Parkinsons disease. Beta-Blocking drugs: These are a class of drugs, which blocks many beta- adrenergic substances such as epinephrine and nor-epinephrine. The main principle of action of the Beta-blockers is the action of the sympathetic nerves of the body (Crosby,Deane and Clarke 2003). As beta-blockers relieves the stress of the heart, it commonly used as the treatment of trachycardia and bradycardia. Critical review of evidence: The article assesses the current state of knowledge of ET therapy. To assess it correctly, the authors categorized all the studies they found into many categories according to the GRADE evidence. The GRADE evidence is used to grade the evidence quality and strength (Louis 2012). The study exclusively included the patients suffering from essential tremors (Patients with Parkinsonian tremor, dystonic tremor and other tremors were exclusively excluded from the study). The article successfully assesses the effects of drugs such as beta-blockers, botulinas toxins, calcium-channel blockers, dopamine agonists and antidepressants and many more drugs on these chosen patients suffering from essential tremor. Randomized control trial methodology was performed on the patients and the data were recorded in the hoc-created collecting form which as described in the Cochranes reviewers handbook. The authors of the article categorized the results into four categories- very low, low, moderate and high according to GRADE (Zesiewicz et al 2010). Efficacy, safety and recommendation of every drugs used in this article was vastly discussed in this article. The research methodology and findings used in this study is relatively accurate. The article is a systematic review, which includes a total number of 43 studies which includes a total of 487 patients with the problem of dystonic tremor and primary writing tremor has been included. The authors of this article could not find the studies with Meta analysis of randomized control trial (Fasano, Bove and Lang 2013). Therefore, they included all the relevant available studies to review. The authors also considered only those cases of tremors, which are confined in just one region of the body. The article reviews many cases in which various combinations of drugs were used, such as Beta-blockers, baclofen, carbamazepine, fluvoxamine and sulpriride. The study discusses the effects of drugs on the patients with dystonia but as no studies with random control trials were used in this study, the interpretation remains incomplete. Mainly, the tremor in Parkinsons disease happens when the person is resting and mainly starts when the person is under stress (Noyce et al 2012). There are many anti-parkinsonian drugs such as levodopa which mainly affects the bradykinesia, rather than helping with the tremors. Beta- blockers are mainly used as the treatment of the tremors related to anxiety and thyroid toxicity along with essential tremors. This article included all studies with randomized controlled trial for beta- blocker therapy and for the placebo patients (Crosby,Deane and Clarke 2003). The study tries to review the safety and efficacy of the beta-blockers as the treatment drug of Parkinsons. The study includes all the patients with idiopathic Parkinsons in two groups, one group included 72 patients who received placebo drugs and the other group was receiving Beta-blockers as drugs. The study used many cross-over trials for the beta-controlled drug (Zappia et al 2013). The study only used a very small number of patients for the trial and the effects of the drugs in comparison with the placebo drugs were low to moderate. Very small number of patients who reported the effect of the beta- control drugs as effective. Identification of strength and limitation of evidence: Strengths: The article has taken a vast number of studies, patients and drugs for the study and has used many randomized control trials for interpreting the results. They have also used the GRADE method to categorize the safety and efficacy of the drugs used for the randomized control trial. The research of this study is well designed( Thenganatt and Jankovic 2014). The studies were designed to obtain data on which the people can rely on. The study describes which drug should be used as the first line treatment and second line treatment for the management of essential tremors. The whole article is well-defined and complete. Limitations: Many additional controls were needed for defining the other possible treatments for the management of Essential Tremor. Strengths: The study discusses many aspects of the treatment of dystonic tremor on a significant number of studies with significant number of patients. The whole finding of the study is well written and the use of the graphs were relevant. Limitations: The main limitation of the study is the lack of the studies with randomized controlled trial. The study only considers those patients suffering from tremor in only one region. The study also excludes the patients who are on combination treatment (Fasano, Bove and Lang 2013). The results on the effects of many drugs such as carbazepine, fluvomaxine, acetazolamine, amitriptyline, baclofen and sulpriride was not very good, so the authors of the paper could not draw any conclusion on this study (Zappia et al 2013). Strengths: The study were based on the randomized controlled trial over the use of the combination of Beta blocker drugs which were compared with placebo drugs placed on the people suffering from Parkinsons (Yu et al 2012). Limitations: The number of the patients used was too small to interpret a result. In addition, no significant results were found. Identification of the relevance, impacts and gaps of the findings: The study is one of the most relevant studies one can found on the treatment of Essential tremor. The study successfully interprets the drugs, which can be used as the first line and second line therapy for Parkinsons (Louis et al 2012). The study is also skillfully determines the safety and efficacy of drugs such as Primidone and propranolol (PRP). The impact of this study over the etratment of Essential tremor would be huge as the physicians could rely only on these kinds of work. The only gap of the finding is that the effects of the drugs were only low to moderate. The study could not find any drug, which can definitely be used as the effective treatment for tremor. The article is not very relevant and is not able give a significant impact on the other studies. There was no study available with randomized control trial and they just included studies with limited result. The authors even excluded many results as it was scattered. The article is also lacks relevancy as there they used very limited number of people to conduct their study and it is not expected to have a correctly interpretive result from such a small study. The main gap of the study is also the usage of the small number of people (Zappia et al 2013). Discussion- shakiness: is there a cure? As discussed in Article 1, drugs such as Primidone, and propranolol (PRP) can be used as the first line therapy to treat essential tremor, though it cannot be used on to the people with young and old age. Drugs like artinolol and sotalol can be used as the second linen treatment for essential tremor. Beta blockers could be used as the first line treatment only in people with definite Essential Tremor. Article 2 discusses the combined effect of surgery and drug such as VIM-DBS (Ventralis Intermedious Nuclei- Different Brain Nuclei) and GPi (Schneider and Deuschl 2014) (Yamamoto et al 2013). The study discusses that the subthalamic area of the brain should be considered for stimulation. According to article 3, all the reporting which includes the adverse report of treatment were reported very poorly, but the use of Beta blockers in the patients leaves some concerns about the efficacy of beta blockers because of the report of the frequency of heart rate decrease. Conclusion: After reviewing the three articles, it can be concluded that, there are not many treatments available for tremor, which depends on the cause. The treatment of tremor depends on the level of severity and disability experienced by the patients. Moreover, the overall effectiveness of the medicines used for tremor remains moderate to very low and the patients frequently discontinues the treatments. References: Baumann, C.R., 2012. Epidemiology, diagnosis and differential diagnosis in Parkinson's disease tremor.Parkinsonism related disorders,18, pp.S90-S92. Crosby NJ,Deane K,and Clarke CE. 2003 Beta-blocker therapy for tremor in Parkinson's disease.Cochrane Database of Systematic Review (3) pp.1-8 Fasano, A., Bove, F. and Lang, A.E., 2013. The treatment of dystonic tremor: a systematic review.J Neurol Neurosurg Psychiatry, pp.jnnp-2013. Gallego, J.., Rocon, E., Belda-Lois, J.M. and Pons, J.L., 2013. A neuroprosthesis for tremor management through the control of muscle co-contraction.Journal of neuroengineering and rehabilitation,10(1), p.36. Jimnez, M.C. and Vingerhoets, F.J., 2012. Tremor revisited: treatment of PD tremor.Parkinsonism related disorders,18, pp.S93-S95. Kim, S.D., Yiannikas, C., Mahant, N., Vucic, S. and Fung, V.S., 2014. Treatment of proximal upper limb tremor with botulinum toxin therapy.Movement Disorders,29(6), pp.835-838. Louis, E.D., 2012. Treatment of essential tremor: are there issues we are overlooking?.Frontiers in neurology,2, p.91. Louis, E.D., Huey, E.D., Gerbin, M. and Viner, A.S., 2012. Depressive traits in essential tremor: impact on disability, quality of life, and medication adherence.European journal of neurology,19(10), pp.1349-1354. Noyce, A.J., Bestwick, J.P., Silveira?Moriyama, L., Hawkes, C.H., Giovannoni, G., Lees, A.J. and Schrag, A., 2012. Meta?analysis of early nonmotor features and risk factors for Parkinson disease.Annals of neurology,72(6), pp.893-901. Schneider, S.A. and Deuschl, G., 2014. The treatment of tremor.Neurotherapeutics,11(1), pp.128-138. Song, I.U., Ha, S.W., Yang, Y.S. and Chung, Y.A., 2015. Differences in regional glucose metabolism of the brain measured with F-18-FDG-PET in patients with essential tremor according to their response to beta-blockers.Korean journal of radiology,16(5), pp.967-972. Thenganatt, M.A. and Jankovic, J., 2014. 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